Enkephalins and endorphins

The met-enkephalin peptide sequence is coded for by the enkephalin gene; the leu-enkephalin peptide sequence is coded for by both the enkephalin gene and the dynorphin gene.

Enkephalins and endorphins

It is not easy to characterize, because each person's Enkephalins and endorphins to BDSM play can be quite different -- and even a single person's reactions to play can vary from scene to scene.

Most people associate BDSM with the physical aspects of the scene: The floggers, whips, rope, and the like. However, there are many mental aspects to a scene as well, and those need to be considered during every scene.

Subspace, in one sense, is much like an hypnotic trance.

Jewish Nobel Prize Winners in Physics

A trance is any period of narrowly-focused attention. If you've been "sucked into" a book or movie, such that the world disappeared for a time, you've been in a trance. During a BDSM scene, as you progressively focus more and more on the physical sensations of play, the entire world may disappear, leaving only you, the Top, and whatever is being done to you.

At the same time, BDSM quite often involves impacts to the body. During a scene, the intense experiences of both pain and pleasure trigger a response of the sympathetic nervous system, which causes a release of epinephrine from the adrenal glands, as well as a dump of endorphins and enkephalins.

These natural chemicals are a part of the body's primal "fight or flight" response. They produce the same effects as a morphine-like drug.

Endorphins - Wikipedia

This dump of morphine-like chemicals into one's bloodstream into increases the pain tolerance of the submissive as the scene becomes more intense -- and also induces a euphoric, ecstatic floating feeling.

Subjectively, subspace is like getting drunk or getting high on drugs. You forget the pain, your problems, all your cares seem to drift away and be obliterated while you're in this state. Some submissives, upon reaching a height of subspace, may lose all sensations of pain, or become incoherent, making safewords useless.

The euphoria of subspace or some parts of it can last anywhere from hours to days after play.

Enkephalins and endorphins

Some people can carry a positive "glow" from play that lasts them for weeks. However, it is also a state of mind that impairs rational thought and decision making skills. It's a state that needs to be monitored carefully for the mental and physical safety and well being of all the parties involved.

If a submissive goes far enough into subspace, they could injure themselves without knowing it, or continue to ask for play that could injure them without their knowledge. If the Top whom they're playing with doesn't understand the dangers of subspace, it can be even more dangerous for the sub.

The experience of subspace is a major reason that subs play within the BDSM world. Aside from exploring desires they've kept hidden from themselves, and experiencing a form of sexually-related play that operates on levels of explicit communication that they've probably never experienced before -- learning to fly in subspace is a powerful and ecstatic experience.

It is literally an incredibly powerful "natural high".Enkephalins, dynorphins, and endorphins are more of a "like" vs a "want" with dopamine. Where are enkephalins, dynorphins, and endorphins made? Hypothalamus and brain stem. Where do the axons of the hypothalamus and brain stem project to?

Periaqueductal gray area, limbic system, and hypothalamus. enkephalin [en-kef´ah-lin] either of two pentapeptides, composed of four identical amino acids and either leucine or methionine, referred to as leu-enkephalin and met-enkephalin.

Schopick to Publish Superb Book

The enkephalins function as neurotransmitters or neuromodulators at many locations in the brain and spinal cord and are involved with pain perception, movement, mood, behavior. Subspace, in one sense, is much like an hypnotic trance. A trance is any period of narrowly-focused attention. If you've been "sucked into" a book or movie, such that the world disappeared for a .

Endorphin and enkephalin. Endorphin and enkephalin are the body's natural painkillers.

Microscopic anatomy

When a person is injured, pain impulses travel up the spinal cord to the brain. The brain then releases endorphins and enkephalins. Opiates (heroin, morphine, etc.).

The human body naturally produces its own opiate-like substances and uses them as neurotransmitters. These substances include endorphins, enkephalins, and dynorphin, often collectively known as endogenous opioids.

Enkephalins and endorphins

An enkephalin (occasionally spelled encephalin) is a pentapeptide involved in regulating nociception in the body. The enkephalins are termed endogenous ligands, as they are internally derived and bind to the body's opioid benjaminpohle.comered in , two forms of enkephalin have been found, one containing leucine ("leu"), and the other containing methionine ("met").

What Are Endorphins? Learn the Benefits, Plus How to Create More